Pediatric Cancer Surgery

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Pediatric Cancer Surgery

1. Types of Pediatric Cancers Requiring Surgery

A. Solid Tumors in the Abdomen & Pelvis

  1. Wilms Tumor (Nephroblastoma)
    • Origin: Kidney
    • TreatmentNephrectomy (kidney removal), sometimes partial kidney removal in smaller tumors.
    • Survival Rate: ~90% with surgery + chemotherapy.
  2. Neuroblastoma
    • Origin: Nerve tissue (commonly in the adrenal glands)
    • Treatment: Tumor resection, often combined with chemotherapy.
    • High-risk Cases: May require bone marrow transplant after surgery.
  3. Hepatoblastoma & Hepatocellular Carcinoma (Liver Cancer)
    • Origin: Liver
    • TreatmentLiver tumor resection or liver transplant in advanced cases.
  4. Rhabdomyosarcoma (Soft Tissue Cancer)
    • Origin: Muscles, tendons, or connective tissues
    • Treatment: Surgery combined with chemotherapy/radiation.

B. Brain & Spinal Cord Tumors

  1. Medulloblastoma (Most Common Brain Cancer in Kids)
    • TreatmentCraniotomy & tumor resection, followed by radiation/chemotherapy.
  2. Gliomas & Astrocytomas
    • Treatment: Partial or total tumor removal; difficult-to-reach tumors may be treated with targeted therapies.
  3. Ependymomas (Brain & Spinal Tumors)
    • TreatmentSurgical removal + radiation therapy for complete eradication.

C. Thoracic (Chest) & Bone Tumors

  1. Ewing Sarcoma & Osteosarcoma
    • Origin: Bones (often in arms, legs, or pelvis)
    • Treatment: Limb-sparing surgery or amputation if necessary, followed by chemotherapy.
  2. Germ Cell Tumors (Testicular or Ovarian Tumors)
    • Treatment: Surgical removal; chemotherapy in malignant cases.

2. Pediatric Cancer Surgery Techniques

A. Open Surgery (Traditional Surgery)

  • Used for large tumors, deep-seated cancers, and complex surgeries like nephrectomy (kidney removal) or hepatectomy (liver tumor removal).

B. Minimally Invasive Surgery (Laparoscopy & Thoracoscopy)

  • Used for small, localized tumors to reduce pain, scarring, and recovery time.
  • Common in kidney, liver, and ovarian tumors.

C. Limb-Sparing Surgery for Bone Cancers

  • In cases of osteosarcoma & Ewing sarcoma, instead of amputation, surgeons remove the affected bone and replace it with an implant or bone graft.

D. Fetal Surgery for Rare Tumors

  • Some tumors, like sacrococcygeal teratoma, can be partially treated before birth to improve survival rates.

3. Post-Surgical Care & Recovery

A. Immediate Postoperative Care

  • ICU Monitoring: Some children may need ventilator support in complex surgeries.
  • Pain Management: Medications to ensure comfort.
  • Nutritional Support: Some children may need feeding tubes if they cannot eat after surgery.

B. Long-Term Follow-Up

  • Physical Therapy: Especially after limb-sparing surgeries or brain tumor removals.
  • Regular Scans (MRI/CT/PET): To detect recurrences or complications.
  • Psychosocial Support: Counseling for both the child and family.

4. Advances in Pediatric Cancer Surgery

  1. Robotic-Assisted Surgery – Offers better precision in delicate areas (e.g., brain & spine tumors).
  2. 3D Imaging & AI in Tumor Mapping – Helps plan complex surgeries with greater accuracy.
  3. Targeted Therapy & Immunotherapy – Combined with surgery for aggressive cancers.

5. Prognosis & Survival Rates

  • Wilms Tumor → ~90% survival with surgery & chemotherapy.
  • Neuroblastoma → Early-stage: 95% survival, High-risk: 50-70%.
  • Osteosarcoma & Ewing Sarcoma → 60-80% if localized, lower if spread.
  • Brain Tumors (Medulloblastoma, Astrocytoma) → 50-80% depending on type & location.
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